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Dr. Boz Reverses Medical Problems with Healthy Keto Living
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FASTING and AUTOPHAGY, A Story of Success.

Diet
Published09 Dec 2019
By Annette Bosworth
8662 Views
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https://www.youtube.com/watch?v=rDzIbkyr5QQ&t=10s
To better understand this story first watch this video on Autophagy and Fasting!

Two very different patients folks!

Both on the keto diet and both achieving levels of ketosis towards better health. Their paths differ and their results improved their health for different reasons. In this show, I talk about the patients, their stories, and their numbers. Learn through their stories about fasting, autophagy, and the Dr. Boz ratio. We wrap things up with a quick tip about their supplements.

Jerry:

Jerry's Fasting Story

68-year old diabetic for 20 years. His HbA1c dropped from 10 to 9.1 in 9 months while he lost 100 lbs. He stopped taking insulin and dropped his BMI from 38.7 to 28.1. Amazing!!

Stacy:

36-year-old mom, a medical provider, healthy and lean. She felt sluggish despite Cross-Fit training. Adult acne brought her to my clinic because she couldn’t get rid of it.  Late-night snacking also increased her blood sugars and likely worsened her acne. 

Stacy's Fasting Story

 

Jerry’s Story of Fasting and Autophagy:

Jerry’s numbers tell a story filled with teachable moments.  His blood glucose towers at 279 before fasting. After fasting for 18 hours, it dropped  to 238. Add in the calculations of what his ketones did and you find his Dr. Boz Ratio [DBR] went from 111.60 to 91.54. I initially recommended a DBR  goal of <100. The DBR reflects insulin production. As he lowers his DBR number, he produces less insulin and the healthier he gets. 

Jerry's Fasting Numbers from Sept. 2-5

A Dr. Boz ratio of 40 or less would dramatically improve Jerry’s situation; a tough challenge indeed. Jerry’s years of bathing in extra insulin created cells used to inflammation.  Those cells replicated thousands of times with a high-insulin state. Over time the cells resist the signal from insulin. They grow deaf to the noise of insulins commanding authority.  Insulin normally orders glucose into the cells and other storage locations. The longer the insulin stays elevated, the less the cells respond to it and the “older” the cells look. 

How do we stop his body from producing insulin?

STOP EATING. Fasting will improve his situation the fastest. Fasting rapidly pushes him into ketosis.

He first ate one meal a day. This improved his chemistry, but his ratios looked like a seesaw: up one moment and then down the next.

Next, he advanced to eating one meal every other day. His ratio went as low as 32. 

Look at his spreadsheet. What can we learn? 

Jerry's Fasting numbers continued

ANSWER: It takes a lot of time between his meals to deliver a steady chemistry improvement. 

Jerry’s years of high insulin resistance led to high triglycerides and being overweight. This means his blood glucose levels cannot be in the 100s unless he eats every other day. Why?

His liver holds a bunch of stored sugars (glycogen).  Unless 48 hours have passed, his glucose numbers rise. Years of stored sugars and elevated triglycerides mean he holds an ample supply of energy that awaits the right chemistry to allow his body to burn it.  

First fasting depletes his glycogen storage. Glycogen provides replacement sugars to burn. A triglyceride breaks down into three chains of fat with a small amount of glucose. Most of the energy stored as triglycerides exits the body as fat-based fuel called a ketone. Splitting triglycerides apart means ketones enter our circulation and a slight rise in blood sugars.

Can Jerry lose weight and restore his metabolism to normal?

Yes – I think so.  He will need to stick to one meal every two days to train his body and do it. It will take months of this improved chemistry state to restore his metabolism.

Metformin, a prescription drug, helps get glucose into the inside of cells and can help Jerry. Without high blood glucose, metformin cannot lower sugars. This makes it quite safe to use to help his progress.

Adding ketones during the fasting period like BHB (beta hydroxybutyrate) will strengthen his mitochondria. The more he uses ketones, and the better he will feel. The more he burns ketones as fuel, the stronger his metabolism will grow. 

Recommendations for Jerry: 

  1. OMEOD = One Meal Every Other Day
  2. Supplement with BHB during times when he feels hungry. 
Jerry's Fasting numbers.3
Jerry's Fasting numbers.3

THE DR BOZ RATIO NEEDS BOTH KETONES AND GLUCOSE:

As in any fraction, one number only gives half the story. Remember, looking only at blood sugars means you left half of the math out of the puzzle.

Dr. Boz Ratio

The “dawn effect” happens every morning. The brain directs the release of glucose which gives us the initial energy we need to begin the day.

Notice the difference in the Dr. Boz Ratio with high blood glucose in the presence of high versus low ketones. High insulin means low ketones. Excess insulin always makes for an unhealthy state. Always. Elevated ketone production happens when insulin is lower than it used to be. Even in diabetics, we see the increased production of ketones when they “reset” their insulin production to less than it used to be. Less insulin means less inflammation. That’s a win!

Any connection between the Dr. Boz Ratio and Autophagy?

Yes. Read more on Autophagy Here

Autophagy means the body cleans and repairs damaged cells. Our body uses these recycled resources to generate healthy, new cells. Lower your Dr oz ratio and watch youthfulness emerge. A high Dr. Boz ratio means high insulin which means no autophagy.

Stacy’s Story of Fasting and Autophagy:

Stacy’s glucose rides well below 100, yet her ketones hover under 1. Her Dr Boz ratio shows that she makes a LOT of insulin to control her glucose. Stacy has 25 years of youth on Jerry, but her DBR is less impressive than Jerry’s. 

Stacy's Fasting Number data sheet from Sept. 19
Get your OWN FREE SPREADSHEET https://bozmd.com/join-the-other-neurons-repairing-their-health-one-ketone-at-a-time/

She’s healthier, younger, and leaner right? Why is her DBR so high? She has had high insulin for a few years. She controls her glucose because her cells still listen to the commanding voice of insulin.  But that insulin still costs her a cellular price. In a word, it charges her body with chronic inflammation. That is the root to her acne. Compared that to Jerry. Jerry’s system wore out. His sugars live in the 200-350 range because his enormous amount of insulin falls on cells that don’t listen anymore. Jerry lives years into his insulin resistance; Stacy just recently entered that chemistry. 

Stacy also just started on Keto. Jerry’s DBR looks better than Stacy’s because his body has had 9 months to practice using ketones. It will take Stacy time to get her numbers settled into a lower DBR. If she fasted for 3 days, she would be there.  I mean only water and salt for 72 hours. Then do keto for the rest of the week and repeat the 72 hour-fast 4-5 more times. This option does not fit Stacy’s life.  

14 days into the Ketogenic diet, she did manage to get her ketones up a little.

Stacy's Fasting Number spread sheet from Oct. 10
Stacy's Fasting Number spread sheet from Sept. 30

What’s holding her back?

Stacy’s flirting with early insulin resistance! Teetering on the edge. Being a mom, a hectic schedule, poor sleep, etc. stirs up enough cortisol to perpetuate the wrong chemistry.  With stress, her glucose levels rise and her ketones fall. She needs to shift the chemistry and this will reverse. Easier said than done with little kids, and intense job and the frustration of her body-acne.

The solution: LET ME DO THE WORK

 Supplement with “ketones-in- a-can.” This will jump-start her metabolism into a ketone burning situation. Ketones in circulation act as a signaling agent.  They send messages to the body while providing a steady fuel to burn. The ketones-in-a-can swirl around our body for 2-3 hours after you drink them. During this time, they signal messages to our cells.  They tell our brains, “I am not hungry.” “I do not have a craving.” 

They decrease swelling and signal the system to not break down muscles for energy.  I

Recommendation for Stacy:

  1. STOP eating at 6PM (no calories or sweeteners after 6PM)
  2. Drink Ketones-in-a-can all day during work for two weeks. 

Sipping on ketones will shift her chemistry away from insulin resistance. Simply adding the ketones will allow her body to burn them instead of glucose.  Without the need for glucose, her cravings will disappear. The first day can be rough, but it gets much better quickly. The ketones will circulate for 2-3 hours.  Whatever she does not use, she will pee out. But 2-3 days of this plan will awaken many of her cells to burn ketones. She will feel an improved energy and less irritation. Meanwhile, decreased insulin will begin to reverse her acne.  This is not fake news. I do not want her on supplements forever, but I do want her body in a healthy chemistry state. This supplement plan works for her life and her early stage of inflammation and insulin resistance. 

Stacy’s metabolism will be much easier to fix than Jerry’s. Each time her body shows an elevated DBR, I will encourage her to drink ketones-in-a-can.  Over time, the metabolism will improve. Her improved choices will follow her improved metabolism. 

Jerry needs this disciplined choices AND the help of extra ketones.  Time will show me how much his body rallies.  


Thank you, Jerry and Stacy, for your willingness to share your stories.  

Watch my video on Jerry and Stacy’s stories by clicking here: https://youtu.be/9b2NqzQq2pI

 

 

P.S. Do muscles break down on Keto? Research shows that ketones and the ketogenic diet actually builds muscle. More on that for a different blog. 

For the latest update on Jerry and Stacy check out this video: https://www.youtube.com/watch?v=9b2NqzQq2pI

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    22 Comments
    1. Avatar
      June Anderson December 10, 2019 at 11:55 AM Log in to Reply

      Hi Dr Boz
      I love your program. As a 70 year old retired teacher, now voluntary worker amongst the poorest of the poor in South Africa, I have a vision to empower the poor to improve their level of health to their maximum potential.
      I have a personal question:
      During a period of intermittent fasting, from 7:30 pm to 11:30 pm, would it enhance or lessen one’s level of ketosis by drinking 2 cups of black coffee each with an added table spoon of MCT oil and ghee butter between 9 and 11 am?
      Warm regards
      June Anderson

      • Avatar
        Dr Boz July 6, 2020 at 11:51 AM Log in to Reply

        June,
        I hope you were watching last night!
        If not here is the replay, I think you may enjoy the third story.
        https://youtu.be/osOUMEqGo2s

    2. Avatar
      Elaine Manuel December 10, 2019 at 1:08 PM Log in to Reply

      I hate the flavor of the ketos in a can.
      Wish you would make another flavor…

      • Avatar
        Dr Boz July 8, 2020 at 7:25 PM Log in to Reply

        Keep your eye open. Something you might like is coming soon.

    3. Avatar
      Eric Jones December 10, 2019 at 2:12 PM Log in to Reply

      Thank you for the update. I needed it. I am also 68 years old and very similar to Jerry’s story. I had been on the KETO diet with intermittent fasting and it worked great, then I got a new job. It requires me going in at 4:00am and working 8 hours/day with only 30 minutes for a lunch break. I couldn’t figure out how to fit thisinto my Keto schedule and the stress made me go back to high carb feel good foods. Now I’ve gained a lot of belly fat back. Jerry’s story has inspired me to go back on the keto schedule and I’ll use keto’s in a can to help me get through. The main take a way from his story is that it will take time to reset my metabolism and I will try to keep that in mind as I go forward. Dr.
      Boz, you are a great practioner and really helpful. Keep up the great work

      • Avatar
        Dr Boz July 8, 2020 at 7:24 PM Log in to Reply

        Thank you !
        Slow and steady you can get there.

    4. Avatar
      Maryann Hites December 13, 2019 at 10:18 PM Log in to Reply

      Great video that I will be studying up on. My husband has mild cognitive impairment and the neurologists and other physicians cannot definitively diagnosis him because his written neuro tests come back so different than what they are looking for and does not fit in their book definitions. I believe this could be for him. But, he is as skinny as as a rail (boomer talk). No matter what he eats, it burns up; but his mind is so forgetful. What do you think? No one can come up with a nutritional answer – even the best nutritionists!

      • Avatar
        Dr Boz July 8, 2020 at 7:20 PM Log in to Reply

        watch this video on how ketones help the brain. https://youtu.be/pBzps7FqleI

      • Avatar
        Dr Boz July 8, 2020 at 7:22 PM Log in to Reply

        Watch this video on how ketones help the brain. https://youtu.be/pBzps7FqleI
        See if that answers any of your questions

    5. Avatar
      David.bone December 21, 2019 at 10:53 PM Log in to Reply

      I’ve been doing keto for about two years. I’m an over the road truck driver.I went from 235 lb to 207lb.I’m kind.of stuck at 207,I think it’s due to lack of exercise.I have no problem eating low carb.Doing 12 hour fast seems to help.

      • Avatar
        Dr Boz July 8, 2020 at 7:09 PM Log in to Reply

        Maybe this video on a weight loss stall will help.
        https://youtu.be/YZeSCRvjXJg

    6. Avatar
      Sara Worth February 26, 2020 at 4:38 AM Log in to Reply

      Hi,
      If we are fasting to a DBR of 40 should that be measured in the morning or can that be at any point of the day?

      • Avatar
        Dr Boz July 8, 2020 at 6:39 PM Log in to Reply

        Your morning numbers are the best. I try to measure and hit 40 before 4:00 pm if not I wait until morning to check.

    7. Avatar
      Bob Linehan April 16, 2020 at 6:10 PM Log in to Reply

      Dear Dr. Boz I am reading “Anyway you Can” for the 2nd time, and am trying to follow all the recommendations, but I am struggling. I am a 74 yr. old male and I started this eating plan in earnest 8 weeks ago. I primarily wanted to lose around 45lbs, but I was equally interested in the other health benefits that the Keto diet is said to provide. In the first 7 weeks, I averaged losing around 2 lbs a week, going from 224.4 lbs to 209. Then, inexplicably, in a period of 3 days, I went back up to 212.6. I have done intermittent fasting several times, eating only from noon until 6:00pm. I have done a 24 hour fast twice. Still, my ketone test strips, usually are around the .5 range, and never seem to get above 1.5. I usually take 2-3 tablespoons of MCT oil daily because I think my biggest problem is getting enough fat on a daily basis. What more should I be doing? I am committed to staying with this, but I don’t believe I have come close to achieving Autophagy yet. Is a 24 fast not enough? Thanks in advance for your reply. I am not on Facebook but I can get YouTube.

      • Avatar
        Dr Boz July 2, 2020 at 6:35 PM Log in to Reply

        Nanna Had stopped losing weight also. Watch her story I think it might help you. https://youtu.be/ugDE9e7xBe8

    8. Avatar
      Ramachandran Chandrasekhar April 28, 2020 at 2:33 AM Log in to Reply

      Dear Dr. Boz:

      I am from India and have started following your YouTube Channel as well as follow you on Twitter.I am greatly impressed with your Dr. Boz ratio and the confidence it has given me from graduating from ‘one who never ever fasted in life’ to ‘my first one day fast’, and then to ‘my first three day fast’ and now on to ‘my fiest five day fast’.

      I have been a diabetic for over 23 years with 100 units of insulin, metformin (2500 mg), Forxiga-10 mg, Januvia 100 mg, Statin 20 mg, Ecosprin 75 mg and Telmisartan 40 mg daily.

      Started Keto since January 2020, OMAD since Feb 2020, did my first one-day-fast in Mar 2020 and now my first three day fast and onto my first 5-day -fast.

      I m raring to tell you more about my journey so that you can use it in your treatment/clinical practice if relevant.

      I would greatly appreciate if you can give me a reply ASAP.

      With kind regards,

      Chander

    9. Avatar
      Erin Dykman May 5, 2020 at 11:29 PM Log in to Reply

      At 75and a Dad of 92 with Alzheimer’s is it too late for me to protect my brain enough to avoid the disease or dementia?

      • Avatar
        Dr Boz July 2, 2020 at 2:45 PM Log in to Reply

        No it is not too late. Watch this video on the brain https://youtu.be/e17iBsKEX4E

    10. Avatar
      Kimberly June 21, 2020 at 4:05 PM Log in to Reply

      Thank you for sharing these stories and for the spreadsheet! My situation closely resembles Stacy. After 36 hours of fasting, I could only get a Ketone reading of 0.2 with glucose ranging from 61-92. I had a “keto coach” earlier this year and when I told him I struggled to get over a 1 for a ketone reading, subsequently he decided not to measure them (which I didn’t think was helpful; how do we assume ketosis?). I learned from your post above that my DBRs suggest high insulin, and like Stacy, I work out 5-6 times per week. Like Stacy, I struggle to get enough sleep. This has stumped me for the last three years. I lost 80 lbs. on low carb in about a year and then inexplicably stalled. I’ve been gaining and losing the same few pounds for the last 3 years, and still have 60 lbs to go. I am 48 years old and have been trying to figure this mystery out before I get too “advanced” in age. I feel that, with your site, I have found a piece to the puzzle. Thank you!

      • Avatar
        Dr Boz July 8, 2020 at 6:25 PM Log in to Reply

        Kimberly,
        maybe you would enjoy this playlist. BEGINNERS— ALL THINGS KETO: http://bit.ly/2yE1Caw
        If may help you get started

    11. Avatar
      Amy Williams October 16, 2020 at 4:55 PM Log in to Reply

      This was great info. I have been OMAD Keto for a year and a half, and have lost 130lbs.That said, I have stalled and also have always struggled to get my ketones above 1.0, even though I am nearly zero carb. I loved using your ketones in a can, but they are never available. Do you have a alternate item that you recommend, or advise as to why my ketones are always low?

      Thanks

      • Avatar
        Dr Boz October 28, 2020 at 5:44 PM Log in to Reply

        Amy,
        Thank you for checking with us.
        We are working on selling the ketones in a can on our web-sight. It should be up and working very soon.

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